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Red light improves photo-aging and reduces wrinkles.

Many women know all about the beneficial effects of high intensity red light on collagen and photo-damage in their skin, but some scientists do not. Lam et al demonstrated that irradiation of fibroblasts with 633-nm wavelength light increased pro-collagen synthesis four-fold from baseline.

Lam TS, Abergel RP, Meeker CA, Castel JC, Dwyer RM, Uitto J. Laser stimulation of collagen synthesis in human skin fibroblast cultures. Lasers Life Sci. 1986;1:61-77.

Human studies confirm such light improves photo-aging and even reduces wrinkles.

Russell BA, Kellett N, Reilly LR. A study to determine the efficacy of combination LED light therapy (633 nm and 830 nm) in facial skin rejuvenation. J Cosmet Laser Ther. 2005 Dec;7(3-4):196-200.

Goldberg DJ, et al. Combined 633-nm and 830-nm led treatment of photoaging skin. J Drugs Dermatol. 2006 Sep;5(8):748-53.

1: J Cosmet Laser Ther. 2005 Dec;7(3-4):196-200.

A study to determine the efficacy of combination LED light therapy (633 nm and 830 nm) in facial skin rejuvenation.

Russell BA, Kellett N, Reilly LR.

Advanced Laser and Dermatologic Surgery Clinics PC, Beaverton, Oregon 97008, USA

BACKGROUND: The use of visible or near infrared spectral light alone for the purpose of skin rejuvenation has been previously reported. A method of light emitting diode (LED) photo rejuvenation incorporating a combination of these wavelengths and thus compounding their distinct stimulation of cellular components is proposed.Objective. To assess the efficacy and local tolerability of combination light therapy in photo rejuvenation of facial skin. METHODS: Thirty-one subjects with facial rhytids received nine light therapy treatments using the Omnilux LED system. The treatments combined wavelengths of 633 nm and 830 nm with fluences of 126 J/cm(2) and 66 J/cm(2) respectively. Improvements to the skin surface were evaluated at weeks 9 and 12 by profilometry performed on periorbital casts. Additional outcome measures included assessments of clinical photography and patient satisfaction scores. RESULTS: Key profilometry results Sq, Sa, Sp and St showed significant differences at week 12 follow-up; 52% of subjects showed a 25%-50% improvement in photoaging scores by week 12; 81% of subjects reported a significant improvement in periorbital wrinkles on completion of follow-up. CONCLUSION: Omnilux combination red and near infrared LED therapy represents an effective and acceptable method of photo rejuvenation. Further study to optimize the parameters of treatment is required.

PMID: 16414908 [PubMed - indexed for MEDLINE]

Related articles

• A study to determine the efficacy of a novel handheld light-emitting diode device in the treatment of photoaged skin.
• J Cosmet Dermatol. 2008 Dec; 7(4):263-7. [J Cosmet Dermatol. 2008]
• The use of light-emitting diode therapy in the treatment of photoaged skin. J Cosmet Dermatol. 2007 Sep; 6(3):189-94. [J Cosmet Dermatol. 2007]
• A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings.
• J Photochem Photobiol B. 2007 Jul 27; 88(1):51-67. Epub 2007 May 1. [J Photochem Photobiol B. 2007]
• ReviewFacial rejuvenation and light: our personal experience. Lasers Med Sci. 2007 Jun; 22(2):93-9. Epub 2006 Nov 23. [Lasers Med Sci. 2007]
• ReviewVisible light treatment of photoaging. Dermatol Ther. 2005 May-Jun; 18(3):191-208. [Dermatol Ther. 2005]

1: J Drugs Dermatol. 2006 Sep;5(8):748-53.

Combined 633-nm and 830-nm led treatment of photoaging skin.

Goldberg DJ, Amin S, Russell BA, Phelps R, Kellett N, Reilly LA.

Skin Laser and Surgery Specialists of NY/NJ, New York, NY 10022, USA. drdavidgoldberg@skinandlasers.com

OBJECTIVES: To evaluate the clinical efficacy and ultrastructural changes in photodamaged skin after combined 633-nm and 830-nm light-emitting diode (LED) treatments. METHODS: Thirty-six subjects received 9 LED treatments over the course of 5 weeks and were subsequently evaluated for final clinical improvement 12 weeks after treatment. Five subjects were also biopsied to determine the ultrastuctural posttreatment changes in collagen fibers. RESULTS: A statistically significant improvement in wrinkles was seen after profilometric analysis. The majority of subjects reported improvements in softness, smoothness, and firmness at all time points. Electron microscopic analysis showed evidence of post-LED treatment of thicker collagen fibers. CONCLUSIONS: 633-nm and 830-nm LED treatments play a role in the treatment of photodamaged skin. LED treatments can be used as either a primary or adjunctive treatment modality.

PMID: 16989189 [PubMed - indexed for MEDLINE]

Related articles

• Clinical trial of a novel non-thermal LED array for reversal of photoaging: clinical, histologic, and surface profilometric results.
• Lasers Surg Med. 2005 Feb; 36(2):85-91. [Lasers Surg Med. 2005]
• Treatment of photoaging with a very superficial Er:YAG laser in combination with a broadband light source.
• J Drugs Dermatol. 2007 Nov; 6(11):1114-8. [J Drugs Dermatol. 2007]
• A study to determine the efficacy of combination LED light therapy (633 nm and 830 nm) in facial skin rejuvenation.
• J Cosmet Laser Ther. 2005 Dec; 7(3-4):196-200. [J Cosmet Laser Ther. 2005]
• ReviewFacial rejuvenation and light: our personal experience. Lasers Med Sci. 2007 Jun; 22(2):93-9. Epub 2006 Nov 23. [Lasers Med Sci. 2007]
• ReviewLight-emitting diodes (LEDs) in dermatology. Semin Cutan Med Surg. 2008 Dec; 27(4):227-38. [Semin Cutan Med Surg. 2008]

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